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Testosterone and cardiovascular disease

0 12 November 2013

A recent Veteran’s Administration study published in JAMA, the Journal of the American Medical Association, has received much media attention, raising fears regarding the use of testosterone replacement in aging men. The study had multiple flaws that limit its usefulness. Some of these flaws include:

  • This was an observational study. These types of studies do not show cause and effect.

  • Subjects in this study were relatively sick with advanced coronary disease.

  • Only 60% of study patients received one follow up blood study to see if their blood levels had improved.

  • Of those that had follow up testosterone levels, the average level was only 332 with the “normal range” being 250-1100. This could hardly be considered a therapeutic level.